Regeneration of islet β-cells in tree shrews and rats
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چکیده
منابع مشابه
Intranuclear Rods in Pancreatic Islet Β-cells
In the course of ultrastructural studies on the morphology of the pancreatic islets of various rodent species used in current diabetes research, intranuclear rod-shaped structures were observed in the $-cells of mice . Since there appeared to be no previous reports on the occurrence of such structures in endocrine pancreas of any species, it was thought worth while to pay some further attention...
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Mangiferin, a xanthonoid found in plants including mangoes and iris unguicularis, was suggested in previous studies to have anti-hyperglycemic function, though the underlying mechanisms are largely unknown. This study was designed to determine the therapeutic effect of mangiferin by the regeneration of β-cells in mice following 70% partial pancreatectomy (PPx), and to explore the mechanisms of ...
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This study aims to determine the incretin effects of Urena lobata leaves extract on the structure and function of rats islet β-cells. This study utilizes male Sprague-Dawley rats divided into 2 control group and 3 test group (n = 5). Diabetic rats were induced with High Fructose Diet (HFD) and single dose intraperitoneal streptozotocin 25 mg/kg bw. Aqueous leaves extract of U. lobata was prepar...
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Human psychological stress is the major environmental risk factor for major depression and certain of the anxiety disorders. Psychological stressors often occur in the context of the adult social environment, and they or the memory formed of them impact on the individual across an extended period, thereby constituting chronic psychosocial stress (CPS). Psychosocial stressors often involve loss ...
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Diabetes is defined as a disease of hyperglycemic metabolic disorder caused by impaired insulin action or low insulin secretion, resulting in the occurrence of vascular complications. Based on this definition, diabetes therapy has long been oriented to correct hyperglycemia against the specific complications of diabetes. This definition has posed some difficulties, however, in understanding of ...
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ژورنال
عنوان ژورنال: Animal Models and Experimental Medicine
سال: 2018
ISSN: 2576-2095
DOI: 10.1002/ame2.12023